Table 1. Correlation between NDRG2 staining and clinicopathologic characteristics in 136 HCC patients.
Variabls | NDRG2 staining | ||
---|---|---|---|
High (n=55) | Low (n=81) | ||
n(%) | n(%) | P value | |
Age (years) | |||
≤50 | 26(47.27%) | 44(54.32%) | 0.420 |
>50 | 29(52.73%) | 37(45.68%) | |
Gender | |||
Male | 42(76.36%) | 67(82.72%) | 0.362 |
Female | 13(23.64%) | 14(17.28%) | |
HBsAg | |||
Negative | 11(20.00%) | 15(18.52%) | 0.830 |
Positive | 44(80.00%) | 66(81.48%) | |
Anti-HCV | |||
Negative | 53(96.36%) | 77(95.06%) | 0.717 |
Positive | 2(3.64%) | 4(4.94%) | |
Liver cirrhosis | |||
No | 9(16.36%) | 17(19.32%) | 0.501 |
Yes | 46(83.64%) | 64(80.68%) | |
Serum AFP, ng/ml | |||
≤20 | 15(27.27%) | 20(24.69%) | 0.735 |
>20 | 40(72.73%) | 61(75.31%) | |
Tumor diameter (cm) | |||
≤5 | 35(63.64%) | 41(50.62%) | 0.133 |
>5 | 20(36.36%) | 40 (49.38%) | |
Microvascular invasion | |||
No | 40(72.73%) | 32(39.51%) | 0.0001 |
Yes | 15(27.27%) | 49(60.49%) | |
Tumor number | |||
Single | 37(67.27%) | 48(59.26%) | 0.344 |
Multiple | 18(32.73%) | 33(40.74%) | |
TNM stage | |||
I | 34(61.82%) | 35(43.21%) | 0.033 |
II -III | 21(38.18%) | 46(56.79%) | |
Edmonson grade | |||
I-II | 45(81.82%) | 51(62.96%) | 0.018 |
III-IV | 10(18.18%) | 30(37.04%) | |
Growth pattern | |||
Expansile | 49(89.09%) | 61(75.31%) | 0.045 |
Infiltrative | 6(10.91%) | 20(24.69%) |
Abbreviations:AFP, alpha-fetoptotein; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus.