Table 1. Ontology analysis of E-regulated functional pathways compared with P-regulated, and combined E/P-regulated pathways in normal human breast.
| E Regulation Summary function | Enrichment score |
|---|---|
| Chemokine signalling | 3.77 |
| Extracellular signalling Hormone response |
2.89 2.85 |
| Extracellular metabolism | 2.34 |
| P regulation Summary function | Enrichment score |
| RNA processing | 9.77 |
| Macromolecule assembly | 3.29 |
| Cell cycle | 3.27 |
| Mitochondrial organisation Cell cycle regulation |
2.97 2.40 |
| Serine peptidase inhibition | 2.21 |
| ECM binding | 2.03 |
| Combined E and P regulation Summary Function | Enrichment score |
| Wound response Cell adhesion Hormone response |
2.68 2.40 2.12 |