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. Author manuscript; available in PMC: 2015 Apr 14.
Published in final edited form as: Curr Biol. 2014 Mar 27;24(8):832–838. doi: 10.1016/j.cub.2014.01.008

Figure 3. RDE-12 and RSD-6 associate with mRNA targeted by RNAi.

Figure 3

(A) Target mRNA preferentially associated with RDE-12 in response to elt-2 RNAi or dpy-28 RNAi. Abundance of mRNA was measured by real-time PCR. (B) Target mRNA preferentially associated with RSD-6 in response to elt-2 RNAi or dpy-28 RNAi. Abundance of mRNA was measured by real-time PCR. The sel-1 mRNA, which was not targeted by RNAi, served as a negative control. (C) Target sel-1 mRNA preferentially associated with RDE-12 in wild-type (WT), rde-10(hj20), rrf-1(pk1417) but not rde-1(ne300) animals. (D) The association of RDE-10 with target mRNAs was reduced in rde-12 mutant animals. All results are shown as mean + standard deviation from at least three independent biological samples assayed in triplicates.