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. 2014 Dec;96(6):1131–1142. doi: 10.1189/jlb.4A0614-283RR

Figure 3. Dependence of the neutrophilic ADRB on CD32(a).

Figure 3.

The importance of CD32(a) in the neutrophilic sADRB (A and C) and mADRB (B and D) was assessed in a 60-min kinetic window using untreated PMNs (black symbols; A and B) and PMNs treated with a CD32(a)-blocking antibody (open symbols; C and D). The reactivities of PMNs were measured against SIP 5 (circles), the SIP-pool (squares), and one NIP (triangles) as representative examples. The data represent the mean ± sd of two experiments using PMNs from two different donors, each in technical duplicates. (A and B) Luminescence intensities were normalized to the reactivity of SIP 5 in each assay and therefore, are presented in arbitrary units. (C and D) The residual percentages compared with the respective kinetics without blocking of CD32(a) are depicted.