Table 3.
Variable | No. of Patients | 3-Year EFS |
5-Year EFS |
P | 3-Year OS |
5-Year OS |
P | 3-Year LC |
5-Year LC |
P | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | |||||
All patients | 57 | 73 | 59 to 83 | 69 | 54 to 81 | 81 | 67 to 89 | 78 | 63 to 87 | 81 | 68 to 90 | 81 | 68 to 90 | |||
Stage | .06 | .02 | .19 | |||||||||||||
1 to 2 | 32 | 81 | 62 to 91 | 81 | 62 to 91 | 93 | 76 to 98 | 88 | 66 to 96 | 87 | 69 to 95 | 87 | 69 to 95 | |||
3 to 4 | 25 | 63 | 41 to 79 | 55 | 31 to 74 | 64 | 40 to 81 | 64 | 40 to 81 | 73 | 49 to 87 | 73 | 49 to 87 | |||
Group | .83 | .65 | .70 | |||||||||||||
I to II | 8 | 73 | 28 to 93 | 73 | 28 to 93 | 88 | 39 to 98 | 88 | 39 to 98 | 83 | 27 to 97 | 83 | 27 to 97 | |||
III to IV | 49 | 73 | 58 to 83 | 69 | 53 to 81 | 80 | 65 to 89 | 76 | 60 to 87 | 81 | 67 to 90 | 81 | 67 to 90 | |||
Site (1) | .32 | .19 | .79 | |||||||||||||
Favorable | 19 | 79 | 54 to 92 | 79 | 54 to 92 | 89 | 64 to 97 | 89 | 64 to 97 | 79 | 54 to 92 | 79 | 54 to 92 | |||
Unfavorable | 38 | 70 | 52 to 82 | 64 | 45 to 79 | 76 | 58 to 88 | 71 | 51 to 84 | 83 | 65 to 92 | 83 | 65 to 92 | |||
Site (2) | .55 | .54 | .31 | |||||||||||||
Orbit | 13 | 92 | 57 to 99 | 92 | 57 to 99 | 100 | 100 to 100 | 100 | 100 to 100 | 92 | 57 to 99 | 92 | 57 to 99 | |||
Parameningeal | 27 | 66 | 45 to 81 | 60 | 37 to 77 | 76 | 53 to 88 | 69 | 45 to 85 | 77 | 56 to 89 | 77 | 56 to 89 | |||
Head and neck | 4 | 50 | 6 to 84 | 50 | 6 to 84 | 75 | 13 to 96 | 75 | 13 to 96 | 50 | 6 to 84 | 50 | 6 to 84 | |||
Bladder and/or prostate | 5 | 80 | 20 to 97 | 80 | 20 to 97 | 80 | 20 to 97 | 80 | 20 to 97 | 100 | 100 to 100 | 100 | 100 to 100 | |||
GI/genitourinary | 3 | 67 | 5 to 95 | 67 | 5 to 95 | 67 | 5 to 95 | 67 | 5 to 95 | 67 | 5 to 95 | 67 | 5 to 95 | |||
Trunk/extremities | 5 | 80 | 20 to 97 | 80 | 20 to 97 | 80 | 20 to 97 | 80 | 20 to 97 | 100 | 100 to 100 | 100 | 100 to 100 | |||
Histology | .32 | .39 | .97 | |||||||||||||
Embryonal/botryoid | 41 | 70 | 54 to 82 | 65 | 47 to 79 | 78 | 61 to 89 | 74 | 55 to 86 | 82 | 66 to 91 | 82 | 66 to 91 | |||
Alveolar/undifferentiated | 16 | 81 | 51 to 93 | 81 | 51 to 93 | 87 | 57 to 97 | 87 | 57 to 98 | 81 | 51 to 93 | 81 | 51 to 93 | |||
Risk group | .04 | .04 | .20 | |||||||||||||
Low | 15 | 93 | 61 to 99 | 93 | 61 to 99 | 100 | 100 to 100 | 100 | 100 to 100 | 93 | 61 to 99 | 93 | 61 to 99 | |||
Intermediate | 42 | 66 | 49 to 78 | 61 | 43 to 75 | 74 | 57 to 85 | 70 | 52 to 83 | 77 | 60 to 87 | 77 | 60 to 87 | |||
Age, years | .60 | .91 | .07 | |||||||||||||
2-10 | 43 | 77 | 61 to 87 | 72 | 53 to 84 | 83 | 68 to 92 | 79 | 61 to 89 | 88 | 74 to 95 | 88 | 74 to 95 | |||
< 2 and > 10 | 14 | 64 | 34 to 83 | 64 | 34 to 83 | 76 | 42 to 92 | 76 | 42 to 92 | 64 | 34 to 83 | 64 | 34 to 83 | |||
Size, cm | .19 | .14 | .28 | |||||||||||||
≤ 5 | 36 | 77 | 60 to 88 | 77 | 60 to 88 | 89 | 72 to 96 | 84 | 64 to 93 | 86 | 69 to 94 | 86 | 69 to 94 | |||
> 5 | 21 | 65 | 41 to 82 | 56 | 29 to 76 | 66 | 38 to 84 | 66 | 38 to 84 | 74 | 47 to 88 | 74 | 47 to 88 |
Abbreviations: EFS, event-free survival; LC, local control; OS, overall survival.