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. 2014 Oct 20;32(33):3762–3770. doi: 10.1200/JCO.2014.56.1548

Table 3.

Treatment Outcomes for All Patients

Variable No. of Patients 3-Year EFS
5-Year EFS
P 3-Year OS
5-Year OS
P 3-Year LC
5-Year LC
P
% 95% CI % 95% CI % 95% CI % 95% CI % 95% CI % 95% CI
All patients 57 73 59 to 83 69 54 to 81 81 67 to 89 78 63 to 87 81 68 to 90 81 68 to 90
Stage .06 .02 .19
    1 to 2 32 81 62 to 91 81 62 to 91 93 76 to 98 88 66 to 96 87 69 to 95 87 69 to 95
    3 to 4 25 63 41 to 79 55 31 to 74 64 40 to 81 64 40 to 81 73 49 to 87 73 49 to 87
Group .83 .65 .70
    I to II 8 73 28 to 93 73 28 to 93 88 39 to 98 88 39 to 98 83 27 to 97 83 27 to 97
    III to IV 49 73 58 to 83 69 53 to 81 80 65 to 89 76 60 to 87 81 67 to 90 81 67 to 90
Site (1) .32 .19 .79
    Favorable 19 79 54 to 92 79 54 to 92 89 64 to 97 89 64 to 97 79 54 to 92 79 54 to 92
    Unfavorable 38 70 52 to 82 64 45 to 79 76 58 to 88 71 51 to 84 83 65 to 92 83 65 to 92
Site (2) .55 .54 .31
    Orbit 13 92 57 to 99 92 57 to 99 100 100 to 100 100 100 to 100 92 57 to 99 92 57 to 99
    Parameningeal 27 66 45 to 81 60 37 to 77 76 53 to 88 69 45 to 85 77 56 to 89 77 56 to 89
    Head and neck 4 50 6 to 84 50 6 to 84 75 13 to 96 75 13 to 96 50 6 to 84 50 6 to 84
    Bladder and/or prostate 5 80 20 to 97 80 20 to 97 80 20 to 97 80 20 to 97 100 100 to 100 100 100 to 100
    GI/genitourinary 3 67 5 to 95 67 5 to 95 67 5 to 95 67 5 to 95 67 5 to 95 67 5 to 95
    Trunk/extremities 5 80 20 to 97 80 20 to 97 80 20 to 97 80 20 to 97 100 100 to 100 100 100 to 100
Histology .32 .39 .97
    Embryonal/botryoid 41 70 54 to 82 65 47 to 79 78 61 to 89 74 55 to 86 82 66 to 91 82 66 to 91
    Alveolar/undifferentiated 16 81 51 to 93 81 51 to 93 87 57 to 97 87 57 to 98 81 51 to 93 81 51 to 93
Risk group .04 .04 .20
    Low 15 93 61 to 99 93 61 to 99 100 100 to 100 100 100 to 100 93 61 to 99 93 61 to 99
    Intermediate 42 66 49 to 78 61 43 to 75 74 57 to 85 70 52 to 83 77 60 to 87 77 60 to 87
Age, years .60 .91 .07
    2-10 43 77 61 to 87 72 53 to 84 83 68 to 92 79 61 to 89 88 74 to 95 88 74 to 95
    < 2 and > 10 14 64 34 to 83 64 34 to 83 76 42 to 92 76 42 to 92 64 34 to 83 64 34 to 83
Size, cm .19 .14 .28
    ≤ 5 36 77 60 to 88 77 60 to 88 89 72 to 96 84 64 to 93 86 69 to 94 86 69 to 94
    > 5 21 65 41 to 82 56 29 to 76 66 38 to 84 66 38 to 84 74 47 to 88 74 47 to 88

Abbreviations: EFS, event-free survival; LC, local control; OS, overall survival.