Table III.
Cellularity and macrophage infiltration of the injured right common carotid artery and non-injured left common carotid artery, expressed as mean ± standard error
| Group | RCCA Injured | RCCA Non-injured | LCCA | |||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| N | Total Cellsa | % Macrophageb | Total Cellsa | % Macrophageb | N | Total Cellsa | % Macrophageb | |
| WT Chow | 3 | 188 ± 25 | 51 ± 9.6c | 207 ± 18 | 54 ± 8.1c | 4 | 347 ± 34d | 1 ± 0.3 |
| WT HC | 6 | 247 ± 17 | 45 ± 5.7c | 245 ± 30 | 37 ± 6.0c | 6 | 331 ± 11d | 2 ± 0.5e |
| TRPC6-/- Chow | 2 | 151 ± 11 | 45 ± 17c | 246 ± 20 | 45 ± 7.7c | 6 | 344 ± 32 | 4 ± 1.1 |
| TRPC6-/- HC | 5 | 213 ± 28 | 52 ± 3.8c | 206 ± 10 | 58 ± 4.6c | 6 | 324 ± 22d | 2 ± 0.3f |
| TRPC5-/- Chow | 6 | 225 ± 17 | 40 ± 3.6c | 211 ± 14 | 37 ± 5.4c | 5 | 255 ± 21 | 3 ± 0.9g |
| TRPC5-/- HC | 5 | 249 ± 18 | 57 ± 3.8c | 200 ± 8 | 55 ± 4.2c | 5 | 250 ± 32 | 7 ± 0.9 |
RCCA = Right common carotid artery
LCCA = Left common carotid artery
HC = High cholesterol
a
Total cell count per 0.05 mm2
b
Percent of total number of cells identified as macrophages per 0.05 mm2
c
Between RCCA injured or RCCA non-injured and LCCA within same study group (P < .05)
d
Between LCCA and RCCA injured or RCCA within same study group (P < .05)
e
Between WT HC LCCA and TRPC5-/- HC LCCA (P < .05)
f
Between TRPC6-/- HC LCCA and TRPC5-/- HC LCCA (P < .05)
g
Between TRPC5-/- Chow LCCA and TRPC5-/- HC LCCA (P < .05)