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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2014 Oct 19;41(6):675–691. doi: 10.1007/s10928-014-9393-x

Figure 10.

Figure 10

Tumor burden model performance for AMG925 orthotopic tumor studies. Symbols are the measured bioluminescence (mean+/−std), and solid lines are the mean of individual model predictions for each dose level. The black bars on the x-axis indicate the duration of dosing events.