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| Primary tumor (pre-treatment) | Primary tumor (post-treatment) | Brain metastasis |
|---|---|---|
| EGFR amplification | EGFR amplification | ATR rearrangement |
| AKT1 amplification | AKT1 amplification | |
| PIK3CA E545G | ||
| KRAS amplification | KRAS amplification | KRAS amplification |
| CCND3 amplification | CCND3 amplification | CCND3 amplification |
| CDK6 amplification | CDK6 amplification | CDK6 amplification |
| TP53 R175H | TP53 R175H | TP53 R175H |
| MTOR R2505 | MTOR R2505 | MTOR R2505 |
