Table 2.
Observed statistical power of QTL additive and epistatic effect detection and effect estimation from simulation with architecture 2
| QTL | Chr:cM | Eff | Pw11 | Pw12 | Pw21 | Pw22 | Pw31 | Pw32 | EffE | PosE | Cov | Width | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1:47 | 1.42 | 99.3 | 88.5 | 88.5 | 88.5 | 88.5 | 100.0 | 1.27 | (.16) | 47.1 | (1.1) | 99.3 | 8.9 |
| 2 | 1:80 | 0.76 | 89.7 | 89.1 | 96.0 | 96.0 | 96.0 | 84.5 | 0.69 | (.30) | 81.7 | (1.1) | 100.0 | 15.3 |
| 3 | 2:49 | -0.04 | 7.1 | 0.0 | 0.0 | 0.0 | 48.1 | 48.1 | -0.11 | (.12) | 54.6 | (1.8) | 97.8 | 21.6 |
| 4 | 3:22 | -0.46 | 64.9 | 53.1 | 54.1 | 54.1 | 61.9 | 61.9 | -0.37 | (.29) | 23.9 | (0.7) | 100.0 | 8.4 |
| 5 | 3:78 | 0.04 | 6.1 | 0.0 | 54.0 | 54.0 | 61.8 | 61.8 | 0.01 | (.04) | 78.2 | (0.6) | 100.0 | 11.6 |
| 6 | 6:5 | -0.06 | 8.2 | 0.0 | 0.0 | 0.0 | 47.8 | 47.8 | -0.08 | (.08) | 2.4 | (0.9) | 100.0 | 15.8 |
| 7 | 7:70 | 0.83 | 100 | 100 | 99.9 | 99.9 | 99.9 | 99.9 | 0.68 | (.04) | 69.2 | (0.7) | 99.0 | 13.3 |
| 8 | 9:63 | 0.13 | 11.1 | 0.0 | 54.0 | 54.0 | 54.0 | 54.0 | 0.01 | (.03) | 61.5 | (2.9) | 99.5 | 16.5 |
| FPR | .08 | 0.0 | 0.0 | 0.0 | .004 | .004 | ||||||||
| #QTL | (std | 2.36) | 4.20 | 3.38 | 4.47 | 4.47 | 5.60 | 5.60 | ||||||
| EPIS | Q1:Q2 | Eff | Pw11 | Pw12 | Pw21 | Pw22 | Pw31 | Pw32 | EffE | |||||
| 1 | 1:2 | 0.49 | 15.9 | 0 | 0 | 0 | 0 | 0 | - | - | ||||
| 2 | 2:4 | 0.99 | 20.9 | 0 | 0 | 0 | 0.7 | 0 | - | - | ||||
| 3 | 2:7 | -0.82 | 45.8 | 23.6 | 23.7 | 12.9 | 12.9 | 8.6 | -0.08 | (.28) | ||||
| 4 | 3:6 | -1.63 | 0 | 0 | 0 | 0 | 47.8 | 47.8 | -0.59 | (.62) | ||||
| 5 | 4:5 | -1.31 | 0 | 0 | 53.9 | 53.9 | 61.7 | 61.8 | -1.17 | (.92) | ||||
| 6 | 4:8 | 1.14 | 0.7 | 0 | 53.9 | 53.9 | 53.9 | 54.0 | 0.79 | (.73) | ||||
| 7 | 5:7 | 0.98 | 0.5 | 0 | 48 | 20.8 | 23.5 | 23.5 | 0.23 | (.41) | ||||
| 8 | 7:8 | -0.98 | 1.7 | 0 | 53.9 | 53.5 | 53.5 | 53.5 | -0.52 | (.49) | ||||
| FPR | .313 | .123 | .125 | .013 | .079 | .030 | ||||||||
The upper panel shows the results for QTL additive effects and the lower panel shows the results for QTL epistatistic effects. Total heritability (h 2) is 0.6 with additive component 0.375 and epistatic component 0.225. Chr:cM is the QTL chromosome and cM position. Q1:Q2 is the interacting QTL pair. Eff is the simulated effect. Pw11 is the observed statistical power from Stage 1 forward search, Pw12 is that from Stage 1 after optimization and elimination; Pw21 is from Stage 2 forward search, Pw22 is from Stage 2 after the final step of backward elimination of QTL; Pw31 and Pw32 are from the similar steps in Stage 3. EffE is the average effect size estimate and PosE is the average position estimate. (Standard deviations are in parentheses.) Cov is the percent coverage for LOD-1 support interval and Width is the average width in cM of the LOD-1 support interval. FPR is false positive rate. #QTL row records average number of QTL found.