Table 2.
Summary of data - part I
| Group | E | A | B | C | D | F |
|---|---|---|---|---|---|---|
| Standard diet - control | Standard diet +0.25 g/day Lenziaren® | Standard diet +0.5 g/day Lenziaren® | Standard diet +1.0 g/day Lenziaren® | Standard diet +2.0 g/day Lenziaren® | Renal diet | |
| Body weight (kg) | ||||||
| Day −30 | 3.617 (0.948) | 3.445 (0.630) | 3.523 (0.880) | 3.342 (0.886) | 3.413 (0.667) | 3.373 (0.536) |
| Day −20 | 3.452 (0.894) | 3.293 (0.654 | 3.405 (0.864 | 3.308 (0.740) | 3.355 (0.700) | 3.212 (0.490) |
| Day 28 | 3.528 (1.003) | 3.448 (0.627) | 3.500 (1.020) | 3.450 (0.745) | 3.445 (0.648) | 2.953 (0.376) |
| CFB Day 28 from Day −30 | −0.088 (0.228) | 0.003 (0.276) | −0.023 (0.225) | 0.108 (0.475) | 0.032 (0.283) | −0.420 (0.172) |
| Mean Days 7-28 | 3.532 (1.012) | 3.430 (0.608) | 3.462 (0.990) | 3.436 (0.738) | 3.465 (0.626) | 2.965 (0.399) |
| CFB Mean Days 7–28 from Day −30 | −0.085 (0.191) | −0.015 (0.248) | −0.061 (0.186) | 0.095 (0.430) | 0.051 (0.266) | −0.409 (0.157) |
| Food consumed (g/day) | ||||||
| Day −14 | 183.6 (53.9) | 200.5 (25.3) | 171.3 (57.4) | 197.7 (45.5) | 220.4 (65.0) | NA |
| Day 28 | 174.8 (47.7) | 200.4 (25.2) | 190.2 (53.4) | 202.2 (42.8) | 189.5 (51.8) | 163.6 (39.0) |
| CFB Day 28 from Day −14 | −8.8 (12.5) | −0.1 (0.2) | 18.9 (19.5) | 4.5 (21.9) | −30.9 (36.9) | NA |
| Mean Days 7-28 | 172.7 (47.0) | 198.2 (21.4) | 181.9 (46.9) | 205.0 (45.7) | 198.1 (49.4) | 160.2 (41.6) |
| CFB Mean Days 7–28 from Day −14 | −10.9 (16.6) | −2.3 (5.6) | 10.6 (17.1) | 7.3 (24.2) | −22.3 (34.4) | NA |
| Serum phosphate concentration (mmol/L) | ||||||
| Day −30 | 1.64 (0.22) | 1.68 (0.36) | 1.56 (0.41) | 1.66 (0.28) | 1.64 (0.42) | 1.76 (0.35) |
| Day 28 | 1.81 (0.26) | 1.71 (0.23) | 1.70 (0.15) | 1.78 (0.23) | 1.68 (0.40) | 1.60 (0.10) |
| CFB Day 28 from Day −30 | 0.17 (0.27) | 0.03 (0.39) | 0.15 (0.33) | 0.12 (0.25) | 0.04 (0.46) | −0.16 (0.27) |
| Mean Days 7-28 | 1.71 (0.26) | 1.70 (0.15) | 1.68 (0.13) | 1.77 (0.22) | 1.70 (0.36) | 1.61 (0.14) |
| CFB Mean Days 7–28 from Day −30 | 0.07 (0.29) | 0.02 (0.27) | 0.12 (0.33) | 0.11 (0.21) | 0.06 (0.44) | −0.15 (0.22) |
| Urine phosphate concentration (mmol/L) | ||||||
| Day −14 | 67.5 (12.4) | 71.8 (36.4) | 77.7 (26.4) | 78.8 (26.4) | 68.7 (16.6) | NA |
| Day 28 | 85.2 (22.8) | 78.7 (19.8) | 70.1 (14.6) | 59.4 (16.3) | 63.0 (12.5) | 61.7 (12.2) |
| CFB Day 28 from Day −14 | 17.7 (17.6) | 6.9 (25.4) | −7.6 (34.6) | −19.5 (22.7) | −5.7 (15.0) | NA |
| Mean Days 7-28 | 86.3 (23.9) | 82.3 (23.5) | 77.4 (14.1) | 71.8 (15.4) | 59.1 (16.6) | 65.8 (17.0) |
| CFB Mean Days 7–28 from Day −14 | 18.8 (15.9) | 10.5 (18.5) | −0.3 (27.1) | −7.0 (16.3) | −9.6 (20.8) | NA |
Data are mean (SD), CFB = change from baseline.
NA = not applicable.