Table 2.
Univariate analysis (Mann–Whitney U test and Fisher exact test) for the development of grade 1–2 chronic GI complications
| Grade 0 | Grade 1-2 | ||
|---|---|---|---|
| Variable | No. | No. | Pvalue |
| Age (y) | |||
| ≤48 | 31 | 17 | 0.815 |
| >48 | 25 | 11 | |
| T-stage | |||
| T1 | 42 | 21 | 1.000 |
| T2 | 14 | 7 | |
| N-stage | |||
| N0 | 50 | 23 | 0.494 |
| N1 | 6 | 5 | |
| Histology | |||
| SCC | 53 | 27 | 1.000 |
| Others | 3 | 1 | |
| Smoking | |||
| None | 51 | 28 | 0.164 |
| Yes | 5 | 0 | |
| Diabetes | |||
| None | 52 | 25 | 0.681 |
| Yes | 4 | 3 | |
| BMI (kg/m2) | |||
| ≤25 | 29 | 16 | 0.817 |
| >25 | 27 | 12 | |
| Body position | |||
| Prone | 56 | 22 | 0.001 |
| Supine | 0 | 6 | |
| RT total dose | |||
| 50.4 Gy | 54 | 21 | 0.005 |
| >50.4 Gy | 2 | 7 | |
| Concurrent chemotherapy | |||
| None | 34 | 9 | 0.020 |
| Yes | 22 | 19 | |
| Chemotherapy regimens | |||
| Cisplatin | 7 | 5 | 0.703 |
| Docetaxel | 15 | 14 |
Abbreviations: GI = gastrointestinal; SCC = squamous cell carcinoma; BMI = body mass index; RT = radiation therapy.