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. 2014 Jul 7;14:224. doi: 10.1186/1472-6882-14-224

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Copyright © 2014 Wu et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Gene expressions and collagen production between SSc dermal fibroblasts and normal controls. (A) Relative transcript levels of COL1A2, COL3A1, CTGF, SPARC and TGF-β1 in three SSc dermal fibroblasts and normal controls. The expression level of each gene in normal controls was normalized to 1. *, P <0.05; **, P <0.001. SF, SSc dermal fibroblast; NF, normal dermal fibroblast. (B) Western blotting analysis of type I collagen (COL1) in the three SSc dermal fibroblasts and normal dermal fibroblasts. (C) Densitometric analysis of western blotting for type I collagen (COL1). Bars showed the mean ± SD results of three paired fibroblast strains (normal and SSc). *, P <0.05; **, P <0.001.