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. 2014 Jul 11;14:509. doi: 10.1186/1471-2407-14-509

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Copyright © 2014 Roselli et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Tumor cell proliferation, apoptosis and blood vessel density in Cd151^+/+and Cd151^−/−mammary tumors. These parameters were assessed by IHC for the cell proliferation marker Ki67 (A, P =0.1533), the apoptosis marker cleaved-caspase 3 (B, P =0.3476), and by immunofluorescence for the endothelial cell specific antigen CD31 (C, P = 0.3035), respectively. Means ± SEM are represented and parametric t-test was used to compare the data. Representative photos of the immunolabelings are also shown. Original magnification: ×200 for Ki67 and Cleaved-caspase 3 and ×100 for CD31.