Table 6.
SNPs with homology to genes of putative immune function mapping near to QTL regions
|
QTL |
Closely mapping SNPs of putative immune function |
|||||||
|---|---|---|---|---|---|---|---|---|
| LG | cM | cM | SNP | GeneID | Length | Hits | E-value | Similarity |
| 1 |
37.3 and 44.1 |
32.1 |
53470_163 |
Heat shock protein 105kd |
615 |
10 |
9.33E-87 |
63.30% |
| |
|
32.9 |
52852_1499 |
Complement c4 |
1991 |
10 |
0 |
62.60% |
| |
|
37.3 |
55086_181 |
Small heat shock protein |
857 |
10 |
6.64E-44 |
81.40% |
| 2 |
43.9, 47.4 and 48.4 |
48 |
16321_60 |
Integrin alpha fg-gap repeat |
127 |
3 |
5.33E-12 |
84.33% |
| 3 |
20.3 and 29 |
27.4 |
134389_297 |
lymphocyte-specific protein tyrosine kinase |
435 |
10 |
2.66E-64 |
89.90% |
| 4 |
0, 0.9, 19.7 and 46.8* |
- |
- |
- |
- |
- |
- |
- |
| 5 |
9.6, 23.8, 38.3 and 43.4 |
9.6 |
98520_125 |
proteasome subunit beta type-6 precursor |
168 |
10 |
9.08E-20 |
93.90% |
| |
|
13 |
111876_59 |
major histocompatibility locus I antigen |
250 |
10 |
9.21E-33 |
89.10% |
| |
|
18 |
53025_556 |
c-type lectin receptor c |
1141 |
10 |
7.40E-106 |
62.40% |
| 6 |
46.9* |
46.9 |
87896_2052 |
complement protein component c7-1 |
2667 |
10 |
0 |
71.50% |
| 7 |
23.4** and 53.7 |
22.6 |
110314_603 |
e3 ubiquitin ligase |
888 |
10 |
2.19E-138 |
66.90% |
| |
|
54.4 |
134666_118 |
immunity related gtpase e4 |
203 |
10 |
2.16E-21 |
66.70% |
| 8 |
23.3 and 54.9 |
54.9 |
31265_40 |
CD22 antigen |
128 |
1 |
1.66E-05 |
71.00% |
| 9 |
32.1 |
- |
- |
- |
- |
- |
- |
- |
| 10 |
26.1, 29.6 and 34.8 |
27.9 |
117051_67 |
ubiquitination factor e4b isoform 2 |
116 |
10 |
9.21E-12 |
97.00% |
| 12 |
31.1 and 37.8 |
- |
- |
- |
- |
- |
- |
- |
| 13 |
19.8, 26.9 and 34.9 |
31 |
17842_95 |
mucin 2 protein |
172 |
10 |
7.15E-17 |
80.70% |
| |
|
31 |
53178_329 |
mucin 2 protein |
2002 |
10 |
0 |
59.10% |
| |
|
31 |
69593_98 |
mucin subtype tracheobronchial |
307 |
10 |
2.79E-45 |
79.30% |
| 14 |
1.9*, 12.5*, 24.1*, 43.9* and 47.1** |
43.9* |
113696_50 |
perforin 1 |
233 |
10 |
1.23E-24 |
67.10% |
| |
|
47.1 |
132709_550 |
chaperonin (HSP60) containing subunit 2 |
922 |
10 |
6.24E-123 |
95.60% |
| 15 |
1.1, 12.5*, 26.7, 28.9, 29.1 and 54.4* |
26.7 |
110434_333 |
t-cell antigen receptor alpha chain c region |
381 |
10 |
6.69E-31 |
74.00% |
| 16 |
23.8 and 39.2 |
23.8 |
115737_104 |
mucin-5b precursor |
347 |
3 |
9.86E-06 |
47.00% |
| 18 |
8.4, 21.5, 35.5*, 48.9 and 49.9* |
18.2 |
133571_269 |
MHC class II antigen beta chain |
391 |
10 |
2.05E-32 |
76.50% |
| |
|
36.7 |
52577_884 |
heat shock protein 70 |
2527 |
10 |
0 |
92.60% |
| 19 |
23.8* |
23.8* |
111569_63 |
tributyltin (tbt)-binding protein |
393 |
10 |
1.91E-46 |
50.50% |
| 20 |
0.8, 1.4, 3, 3.3*, 7.9, 9.4, 11.1*, 20.3 and 21.6 |
- |
- |
- |
- |
- |
- |
- |
| 21 |
47.1 and 51.1* |
45.2 |
2465_218 |
ubiquitin-conjugating enzyme e2 c |
279 |
10 |
1.75E-31 |
95.30% |
| 22 |
6, 6.4, 22.3 and 23.2 |
22.9 |
83239_350 |
fish virus induced trim protein |
447 |
10 |
3.79E-66 |
65.10% |
| 23 |
0***, 0.9 and 27.4 |
0.7 |
55156_84 |
dermatin sulphate epimerase |
378 |
10 |
4.94E-66 |
80.30% |
| |
|
23.2 |
554_399 |
dipeptidyl-peptidase 7 |
502 |
10 |
1.19E-67 |
76.00% |
| 24 |
49, 51.5 and 55.9* |
- |
- |
- |
- |
- |
- |
- |
| 25 | 46.1 | - | - | - | - | - | - | - |
GeneID, identity allocated by blast2go using consensus annotations for the top hits. Length, length of query contig sequence. Hits, number of sequences found to match query (maximum 10). E-value, minimum e-value (probability of alignment occurring by chance) recorded for a hit. Similarity, percent mean similarity recorded across hits. *, P <0.05; **, P <0.01; ***, P <0.001 after Bonferroni correction.