Table 4.
Postoperative data of the two study groups
| Categories | Non-etomidate group | Etomidate group | P value |
|---|---|---|---|
| Number of patients |
1,279 |
1,775 |
|
| CRP, mg/L |
|
|
|
| Missing |
140 (10.9%) |
80 (4.5%) |
|
| Day 1 |
76.9 ± 1.2 |
77.0 ± 1.0 |
0.924 |
| Day 2 |
183.8 ± 2.6 |
194.1 ± 2.2 |
0.382 |
| Day 3 |
205.9 ± 3.8 |
211.5 ± 3.4 |
0.316 |
| Day 4 |
189.7 ± 4.9 |
187.9 ± 4.3 |
0.340 |
| Day 5 |
166.6 ± 6.5 |
150.9 ± 4.9 |
0.306 |
| PCT, ng/mL |
|
|
|
| Missing |
732 (57.2%) |
963 (54.2%) |
|
| Day 1 |
4.1 ± 0.4 |
5.6 ± 0.5 |
0.053 |
| Day 2 |
8.4 ± 0.9 |
10.0 ± 1.1 |
0.090 |
| Day 3 |
7.9 ± 0.9 |
8.8 ± 0.9 |
0.312 |
| Day 4 |
6.3 ± 0.9 |
6.6 ± 0.9 |
0.673 |
| Day 5 |
4.7 ± 0.6 |
5.7 ± 0.7 |
0.254 |
| Leukocytes, 103/μL |
|
|
|
| Missing |
73 (5.7%) |
63 (3.5%) |
|
| Day 1 |
12.8 ± 0.2 |
11.7 ± 0.1 |
0.061 |
| Day 2 |
11.9 ± 0.2 |
11.7 ± 0.2 |
0.327 |
| Day 3 |
11.9 ± 0.3 |
11.7 ± 0.3 |
0.899 |
| Day 4 |
11.5 ± 0.4 |
11.3 ± 0.4 |
0.969 |
| Day 5 |
11.7 ± 0.5 |
11.3 ± 0.4 |
0.776 |
| CK |
|
|
|
| U/L |
1347 ± 71 |
1642 ± 86 |
0.002 |
| Missing |
390 (30.5%) |
226 (12.7%) |
|
| CK-MB |
|
|
|
| U/L |
10.1 ± 0.2 |
10.0 ± 0.2 |
0.801 |
| Missing |
444 (34.7%) |
292 (16.4%) |
|
| Troponin |
|
|
|
| μg/L |
9.8 ± 0.6 |
11.5 ± 0.5 |
0.004 |
| Missing |
391 (30.5%) |
230 (12.9%) |
|
| Hemodialysis |
|
|
|
| N |
8.8% |
10.2% |
0.190 |
| Hours |
105 ± 12 |
112 ± 10 |
0.861 |
| SOFA score |
|
|
|
| Missing |
655 (51.2%) |
884 (49.8%) |
|
| Day 1 |
7.9 ± 0.1 |
7.9 ± 0.1 |
0.340 |
| Day 2 |
7.2 ± 0.2 |
7.3 ± 0.1 |
0.122 |
| Day 3 |
7.4 ± 0.2 |
7.3 ± 0.2 |
0.697 |
| Day 4 |
8.3 ± 0.3 |
8.2 ± 0.2 |
0.859 |
| Day 5 |
8.8 ± 0.3 |
8.4 ± 0.3 |
0.394 |
| Hospital days |
17.4 ± 0.6 |
18.7 (0.6%) |
0.250 |
| ICU days |
2.5 ± 0.1 |
2.6 ± 0.1 |
0.857 |
| ICU discharge |
|
|
|
| Day 1 |
694 (56%) |
883 (51%) |
0.013 |
| Day 2 |
158 (13%) (∑852; 68%) |
297 (17%) (∑1180; 68%) |
0.937 |
| Day 3 |
151 (12%) (∑1003; 80%) |
205 (12%) (∑1385; 80%) |
0.795 |
| Day 4 |
80 (6%) (∑1083; 87%) |
115 (7%) (∑1500; 87%) |
0.898 |
| Day 5 |
39 (3%) (∑1122; 90%) |
51 (3%) (∑1551; 90%) |
0.776 |
| ICU re-admission |
70 (5.5%) |
102 (5.8%) |
0.746 |
| 7-day mortality |
39 (3.0%) |
64 (3.6%) |
0.401 |
| 30-day mortality |
66 (5.2%) |
106 (6.0%) |
0.337 |
| Overall in hospital mortality | 82 (6.4%) | 121(6.8) | 0.657 |
Continuous variables are given as mean ± standard error, and categorical variables are presented as number (percentage). CK, creatinkinasis; CML, Cormack and Lehane; CRP, C-reactive protein; ICU, intensive care unit; PCT, procalcitonine; SOFA, Sequential Organ Failure Assessment.