Table 1.
Baseline physiological and clinical data with comparison for survival at 30 days and 6 months
| Characteristic | Baseline |
30-day mortality |
6-month mortality |
||
|---|---|---|---|---|---|
| Survivors | Nonsurvivors | Survivors | Nonsurvivors | ||
| Mortality |
60 |
40 (67%) |
20 (33%) |
31 (52%) |
29 (48%) |
| Physiology |
|
||||
| Age (years) |
62 ± 15 |
60 ± 16 |
65 ± 13 |
60 ± 17 |
65 ± 13 |
| Female (%) |
50 |
30 |
20 |
21.7 |
28.3 |
| SOFA score |
11 ± 4 |
10 ± 4* |
13 ± 3* |
10 ± 4* |
12 ± 4* |
| MAP (mmHg) |
62 ± 13 |
63 ± 15 |
60 ± 8 |
63 ± 13 |
61 ± 61 |
| Hemoglobin (g/dl) |
10.1 ± 1.6 |
10.2 ± 1.6 |
9.8 ± 1.6 |
10.4 ± 1.6 |
9.7 ± 1.5 |
| NE dose (μg/kg/minute) |
0.2 (0.06 to 0.34) |
0.15 (0.04 to 0.475) |
0.225 (0.08 to 0.32) |
0.18 (0.07 to 0.5) |
0.2 (0.1 to 0.3) |
| Vasopressin (u/minute) |
0.04 (0.03 to 0.04) |
0.04 (0.03 to 0.04) |
0.04 (0.03 to 0.04) |
0.04 (0.03 to 0.04) |
0.04 (0.03 to 0.04) |
| ScvO2 (%) |
72 ± 11 |
70 ± 13 |
75 ± 8 |
72 ± 11 |
72 ± 12 |
| PaO2/FiO2 (mmHg) |
195 (128 to 290) |
247 (153 to 310)* |
163.5 (113 to 199)* |
248.5 (76 to 300) |
175 (124 to 260) |
| pCO2 (mmHg) |
40 ± 12 |
38 ± 9* |
45 ± 14* |
38 ± 11 |
43 ± 2 |
| pH |
7.29 ± 0.1 |
7.3 ± 0.1 |
7.27 ± 0.1 |
7.3 ± 0.1 |
7.29 ± 0.1 |
| Lactate (mmol/l) |
3 ± 2.8 |
2.4 ± 0.4* |
4.2 ± 0.6* |
1.45 (1 to 3.78) |
2.4 (1.4 to 4.2) |
| Creatinine (mg/dl) |
1.9 ± 1 |
2.1 ± 1.2 |
1.6 ± 0.7 |
1.84 ± 0.9 |
2 ± 1.2 |
| Troponin T (ng/ml) |
0.03 (0.01 to 0.16) |
0.03 (0.01 to 0.2) |
0.03 (0.01 to 0.12) |
0.025 (0.01 to 0.2) |
0.03 (0.01 to 0.1) |
| Clinical |
|
||||
| Respiratory issues |
18 (30%) |
12 |
6 |
7 |
11 |
| Coronary artery disease |
8 (13%) |
7 |
1 |
3 |
5 |
| Chronic renal failure |
7 (12%) |
5 |
2 |
4 |
3 |
| Acute kidney injury |
25 (42%) |
17 |
8 |
12 |
13 |
| Mechanical ventilation | 39 (65%) | 21* | 18* | 15* | 24* |
Data presented as n (%), mean ± standard deviation or median (interquartile range). *P <0.05 by analysis of variance. MAP, mean arterial pressure; NE, noradrenaline; pCO2, partial pressure of carbon dioxide; PaO2/FiO2, arterial partial pressure of oxygen/fraction of inspired oxygen ratio; ScvO2, central venous oxygen saturation; SOFA, Sequential Organ Failure Assessment.