Table 2.
Direct antiviral action of plant extracts against influenza A virus A/Teal/Tunka/7/2010 (H3N8)
| Extract | NI ± SD * | ID50% ** |
|---|---|---|
|
Gentiana decumbens, 1% extract |
1.4 ± 0.7 |
- |
|
Hypecoum erectum, 1% extract |
4.8 ± 0.2 |
8.6 |
|
Polygonum bistorta, 1% extract |
1.6 ± 0.1 |
- |
|
Terminalia chebula, 0.5% extract |
4.9 ± 0.2 |
13.4 |
|
Momordica cochinchinensis, 0.5% extract |
5.1 ± 0.3 |
2.7 |
| DEVA-5, 1% extract |
1.6 ± 0.4 |
- |
| H3N2 Abs, diluted as 1:100 | 93.9 ± 0.7 | 59.1 |
* - approximately 1 × 105 PFU of A/Teal/Tunka/7/2010 (H3N8) were used for the NI assay.
** - approximately 200 PFU of A/Teal/Tunka/7/2010 (H3N8) were used for the PRNT assay.
The neutralisation index (NI) was estimated as the quotient of the virus concentration in the water-treated sample to the virus concentration in the test sample. The 50% inhibition dose was estimated using probit analysis as the maximal reciprocal dilution of extract that inhibited the formation of plaques by 50%.