Table 3.
Regimen, spectrum and type of infection
| Cases with infections | Number of infectious episodes | Focus of infection | Opportunistic infections | Identified pathogen | Number of CTC grade 3 + 4 infections* | |
|---|---|---|---|---|---|---|
|
Rituximab monotherapy (n = 23) |
4 |
4 |
Pneumonia (n = 1) |
2 |
none (n = 2) |
3 |
| viral (n = 2) | ||||||
| Opp. Inf. (n = 2) | ||||||
| Bronchitis (n = 1) | ||||||
|
R-CHOP/R-CHOEP (n = 88) |
53 |
80 |
UTI (n = 12) |
15 |
none (n = 47) |
66 |
| bacterial (n = 17) | ||||||
| URTI (n = 11) | ||||||
| Opp. inf. (n = 12) |
viral (n = 15) |
|||||
| Opp. Pneumonia (n =5) |
fungal (n = 3) |
|||||
| Bronchitis (n = 5) |
||||||
| FUO (n = 22) |
||||||
| Sepsis (n = 2) |
||||||
|
R-FC/R-FCM (n = 8) |
6 |
9 |
Bronchitis (n = 3) |
2 |
none (n = 4) |
4 |
| bacterial (n = 3) | ||||||
| OppInf (n = 2) | ||||||
| viral (n = 2) | ||||||
| UTI (n = 1) | ||||||
| FUO (n = 2) | ||||||
| Sepsis (n = 1) | ||||||
|
R-GMALL/R-DHAP (n = 9) |
7 |
19 |
UTI (n = 2) |
2 |
none (n = 12) |
16 |
| bacterial (n = 5) | ||||||
| Pneumonia (n = 2) | ||||||
| fungal (n = 2) | ||||||
| FUO (n = 8) | ||||||
| Sepsis (n = 4) | ||||||
| URTI (n = 1) | ||||||
| Opp Pneumonia (n = 1) | ||||||
| Sinusitis (n = 1) | ||||||
|
R-Gemcitabine (n = 1) |
1 |
1 |
Pneumonia (n = 1) |
none |
0 |
1 |
|
R-IMVP16 (n = 2) |
2 |
3 |
FUO (n = 1) |
1 |
none (n = 2) |
3 |
| viral (n = 1) | ||||||
| URTI (n = 1) | ||||||
| OppInf (n = 1) | ||||||
|
R-Bendamustine (n = 4) |
1 |
3 |
Pneumonia (n = 1) |
None |
none (n = 1) |
3 |
| Sepsis (n = 1) |
bacterial (n = 2) |
|||||
| UTI (n = 1) |
||||||
|
R-Other (n = 6) |
6 |
19 |
FUO (n = 4) |
1 |
none (n = 13) |
19 |
| Norovirus (n = 1) |
viral (n = 1) |
|||||
| Diarrhea (n = 3) |
bacterial (n = 4) |
|||||
| Pneumonia (n = 4) |
fungal (n = 1) |
|||||
| Sepsis (n = 3) | ||||||
| Bronchitis (n = 1) | ||||||
| URTI (n = 1) | ||||||
| Sinusitis (n = 1) | ||||||
| Opp. Inf. (n =1) | ||||||
UTI = urinary tract infection, URTI = upper respiratory tract infection, FUO = fever of unknown origin, Opp = Opportunistic.
*in 35 cases more than one infection occured.