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. 2014 Jul 5;11:57. doi: 10.1186/1742-4690-11-57

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Copyright © 2014 Jacobs et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Genes with 1.5 fold or greater difference in expression between Ag and Ag + Ant. Fold change was calculated and Ag + Ant was subtracted from Ag treatment. Data were then sorted from highest to lowest and 1.5 fold or greater differences. Replicate values for up-regulated and down-regulated genes are displayed in a heat map (A). Expression of up-regulated (B) and down-regulated (C) genes with medians from individual treatments are shown (Unstim = Unstimulated, Ag = Agonist, Ag + Ant = Agonist + Antagonist, Ant = Antagonist alone). p-Values were determined by Kruskal-Wallis followed by Dunn’s Multiple Comparisons Test, *** = p < 0.001.