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. 2014 Jul 5;11:57. doi: 10.1186/1742-4690-11-57

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Copyright © 2014 Jacobs et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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IPA Comparison analysis of gene array data. IPA comparison analysis was completed comparing Ag to Ag + Ant to Ant treatments. Displayed are molecular and cellular functions and physiological system development functions that are associated with cellular signaling and function and proliferation (A). Each pair of bars displays the most significantly associated function within that category that is over-represented in the dataset. The larger the bar, the more strongly over-represented those functions were in the dataset. The p-values were determined by right-tailed Fisher’s exact test with a p < 0.05 considered significant. Only over-represented functions or ones that have more associated molecules than those are expected by chance are significant. Activation z-scores (calculated as described) for the 10 functions listed in Figure 6 that were associated with T cell signaling and function are displayed (B). The p-values were determined by One-way analysis of variance followed by Tukey’s multiple comparison test. *p < 0.05, **p < .01, ***p < .005.