Table 4.
Gender | Age | Group | Genotype (Counts) | χ2 | p (df = 2) a | HWE | Allele (Counts) | χ2 | p (df = 1) | OR (95% CI) | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs4977574 | AA | GA | GG | A | G | ||||||||
Male | <65 | Case (n = 254) | 50 | 136 | 68 | 0.26 | 236 | 272 | 1.45 (1.11–1.90) | ||||
Control (n = 191) | 53 | 107 | 31 | 8.63 | 0.04 | 0.08 | 213 | 169 | 7.55 | 0.006 | |||
≥65 | Case (n = 161) | 36 | 84 | 41 | 0.64 | 156 | 166 | 1.35 (0.88–2.05) | |||||
Control (n = 60) | 15 | 37 | 8 | 3.75 | 0.30 | 0.07 | 67 | 53 | 1.91 | 0.16 | |||
Female | <65 | Case (n = 89) | 18 | 39 | 32 | 0.39 | 75 | 103 | 1.87 (1.30–2.70) | ||||
Control (n = 169) | 52 | 91 | 26 | 14.64 | 0.0002 | 0.20 | 195 | 143 | 11.31 | 0.0008 | |||
≥65 | Case (n = 81) | 18 | 46 | 17 | 0.27 | 82 | 80 | 1.16 (0.72–1.88) | |||||
Control (n = 57) | 15 | 32 | 10 | 0.44 | 0.63 | 0.42 | 62 | 52 | 0.38 | 0.54 |
a: p values were adjusted by age, sex, smoking, HDL-C and LDL-C.