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. 2014 Oct 9;15(10):18148–18161. doi: 10.3390/ijms151018148

Figure 3.

Figure 3

TPX2 knockdown inhibits cell proliferation and viability in HCC. (A) Hep3B and HepG2 cells that were transfected with non-targeting (NT) shRNA and TPX2 shRNA, respectively, were subjected to WB for TPX2. n = 6; * p < 0.05 by t test; (B) Cell proliferation as measured by BrdU incorporation was inhibited by TPX2 knockdown in Hep3B and HepG2 cells. * p < 0.05 by t test; n = 3 repeats with similar results; (C) As assessed by MTT assays, TPX2 knockdown was found to reduce the viability of Hep3B and HepG2 cells. * p < 0.05 by two-way ANOVA; n = 3 repeats with similar results. Values are depicted as Mean ± SEM.