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Schematic representation of the different stages of prostate cancer (PCa) tumour initiation and progression. Monocarboxylate transporter 1 (MCT1) is expressed in both non-neoplastic and malignant glands, whereas MCT2 is increased from benign to prostate intraepithelial neoplasia (PIN) lesions and malignant glands. MCT4 is only expressed in malignant glands, and its expression is associated with poor prognosis for patients.
