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. 2014 Jul 9;15(1):579. doi: 10.1186/1471-2164-15-579

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© Przybytkowski et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Densities of breakpoints on individual chromosomes in all tumors. Heat map showing distribution of breakpoints within genomes. Total number of breakpoints per each chromosome was normalized to the size of the chromosome and it is expressed as numbers of breaks per 100 Mb. Tumors are aligned from the least aberrant (top) to the most aberrant (bottom). Tumor ploidies are indicated on the left: tumors with diploid flow sorting profiles are marked as follows: diploid tumors (D), tetraploid tumor (T), diploid or tetraploid (D/T); tumors with aneuploid flow sorting profiles are marked with A. The color code in the tumor number column corresponds to the clinical subtype: blue = ER+; pink = HER2+; grey = TNBC.