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. 2014 Jul 11;14:385. doi: 10.1186/1471-2334-14-385

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Copyright © 2014 Bruyère et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Organ failure kinetic expressed as global SOFA score value (panel A) and the cardiovascular SOFA score (panel B) daily measurements over the first week of treatment in the subset of patients (n = 30) who received empirical echinocandin therapy according to local guidelines without any proven IC thereafter. The patients were classified as “responders” if SOFA decreased by more than 1 point during the first 5 days of therapy (n = 18). Otherwise, they were considered as “non responders” (n = 12). D: day; SOFA: sequential organ failure assessment; IC: invasive candidiasis; R: responders; NR: non responders.