Table 1.
Antibiotic susceptibility patterns of K. oxytoca LMM-SA26, E. coli LMM-SA26Tc transconjugant, and E. coli MKD135 recipient.
| Antibiotics tested | MIC (mg/liter) for | ||
|---|---|---|---|
| K. oxytoca LMM-SA26 | E. coli LMM-SA26Tc | E. coli MKD135 | |
| Cefotaxime | 32 | 16 | 0.064 |
| Cefotaxime/clavulanic acida | 8 | 4 | 0.125 |
| Ceftazidime | >256 | 125 | 0.025 |
| Ceftazidime/clavulanic acida | 32 | 8 | 0.25 |
| Aztreonam | 8 | 4 | 0.25 |
| Imipenem | 8 | 4 | 0.064 |
| Ertapenem | >64 | 16 | 0.032 |
| Meropenem | 16 | 16 | 0.064 |
| Gentamicin | >64 | 2 | 0.5 |
| Amikacin | 64 | 2 | 0.5 |
| Tobramycin | 16 | 1 | 0.125 |
| Nalidixic Acid | 1 | 0.064 | 1 |
| Ciprofloxacin | 2 | 0.125 | 0.25 |
| Colistin | 1 | 0.25 | 0.25 |
| Tigecycline | 0.25 | 0.125 | 0.125 |
| Others test | |||
| DDST | + | + | − |
| MHT | + | + | − |
| Ertapenem + boronic acidb | + | + | − |
| Imipenem + EDTAc | − | − | − |
aClavulanate was used at a fixed concentration of 4 mg/liter. bThe test was considered positive when boronic acid exhibited inhibitory effects increasing the bacterial growth-inhibitory zone to ≥5 mm around the ertapenem disk. cThe test was considered negative when EDTA did not increase the bacterial growth-inhibitory zone (≥5 mm) around the imipenem disk. DDST: double disk synergy test; MHT: modified Hodge test.