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. 2014 Nov 11;8:915. doi: 10.3389/fnhum.2014.00915

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Copyright © 2014 Hänggi, Fövenyi, Liem, Meyer and Jäncke.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between the connectivity ratio derived from the 90 ROIs connectivity matrix and brain size in the gender-pooled sample (N = 138) as revealed by a cubic function. The connectivity ratio was computed based on the number of reconstructed interhemispheric connections (streamlines) divided by the number of intrahemispheric connections. Brains of intermediate size showed the predicted negative association of these measures. However, the smallest (mainly female) and the largest (all male) brains do not follow our predictions. These subjects showed a positive instead a negative association between the connectivity ratio and TBV.