Table 2.

Changes in key variables during the hyperinsulinaemic-hypoglycemic clamp under normoxic and hyperoxic conditions.

	Study Timepoint		Change Clamp - Baseline
	Baseline	Clamp
PaO2 (mmHg)
Normoxia	108±3	122±3	14±3
Hyperoxia	110±6	424±39*a	313±38*
PaCO2 (mmHg)
Normoxia	41±1	41±1a	−1±1
Hyperoxia*	41±1	39±1a	−2±1
Insulin (uU/mL)
Normoxia	4±1	132±8a	128±8
Hyperoxia	4±1	132±7a	128±7
Glucose (umol/mL)
Normoxia	5.4±0.1	3.4±0.1a	−2.0±0.1
Hyperoxia	5.5±0.1	3.3±0.1a	−2.2±0.1
Glucose Infusion Rate (umol/kg FFM/min)
Normoxia	----	28±4a	28±4
Hyperoxia	----	37±3*a	37±3*
Norepinephrine (pg/mL)
Normoxia	206±20	355±40a	149±29
Hyperoxia	203±19	312±39a	109±29
Epinephrine (pg/mL)
Normoxia	28±4	748±101a	720±99
Hyperoxia	32±6	577±85*a	545±84*

Mean±SE, n=10

Effect of Condition: *p<0.05 vs Normoxia

Effect of Timepoint: ^ap<0.05 vs Baseline