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Stress reduces epidermal hyperplasia and inflammation in acute allergic contact dermatitis (ACD) mice. (a–c) Representative hematoxylin and eosin sections of normal or ACD mice, with or without superimposed stress. (d–f) Proliferating cell nuclear antigen (PCNA) immunostaining in parallel sections (see a–c). (g) Quantification of epidermal hyperplasia (thickness) of nucleated cell layers, PCNA+cells (PNA+cells/unit length of basal layer), and inflammatory cell density/mm2. Bar=20 μm.
