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. 2014 Aug 5;13(11):4910–4918. doi: 10.1021/pr500557n

Figure 1.

Figure 1

Experimental design workflow. HCT116 cell were silenced with siITGA3 siRNAs, whereas NOX4 was inhibited in SW620 cells with siRNAs or VAS2870. Proteins samples were digested, labeled with iTRAQ reagents, fractionated, and analyzed with a nanoAcquity UPLC coupled to a Q-Exactive mass spectrometer.