Scheme 1.
A chemoenzymatic approach for the synthesis of 2,5-disubstituted pyrrolidines by employing an ω-transaminase (TA) and a monoamine oxidase (MAO-N).
A chemoenzymatic approach for the synthesis of 2,5-disubstituted pyrrolidines by employing an ω-transaminase (TA) and a monoamine oxidase (MAO-N).