. 2014 Sep 29;29(12):2670–2679. doi: 10.1093/humrep/deu245

Table V.

Hatching configuration and time to first breach in zona-intact, laser zona-opened and laser zona-thinned mouse embryos, as assessed by TLM.

Time to first breach Mean hours post hCG (±SD) (Min; Max)	Group
Time to first breach Mean hours post hCG (±SD) (Min; Max)	Control zona-intact (ZI)	Laser zona-opened (ZO)	Laser zona-thinned (ZT)
Breach site
PTE	102.3 (3.3) (98.3; 106.3)	93.2 (6.9) (85.7; 107.0)	103.0 (7.6) (95.6; 114.5)
Overall group comparison^a
Pairwise comparisons^b	P = 0.0049
ZI versus ZO	P = 0.0030
ZI versus ZT	NS
ZO versus ZT	P = 0.0145
PMTE	99.6 (9.1) (88.1; 116.9)	92.1 (3.8) (86.5; 101.2)	99.7 (6.2) (89.7; 109.8)
Overall group comparison^a
Pairwise comparisons^b	P = 0.0056
ZI versus ZO	P = 0.0022
ZI versus ZT	NS
ZO versus ZT	P = 0.0176
DMTE	99.6 (5.2) (88.9; 110.3)	92.4 (4.7) (81.2; 97.8)	98.3 (6.1) (86.8; 107.5)
Overall group comparison^a
Pairwise comparisons^b	P = 0.0003
ZI versus ZO	P = 0.0001
ZI versus ZT	NS
ZO versus ZT	P = 0.0020

^aANOVA to test for group differences.

^bT-Test for pairwise group comparisons.