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. 2014 Nov 5;9:5131–5141. doi: 10.2147/IJN.S71074

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© 2014 Duan et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effects of Nano-SiO₂ on the production of CRP and cytokines in HUVECs.

Notes: The expression of CRP (A) and the production of TNF-α (B), IL-1β (C), and IL-6 (D) were significantly increased in a dose-dependent manner. ANOVA followed by the LSD method are used for the data analysis. Data are expressed as the mean ± standard deviation from three independent experiments (*P<0.05).

Abbreviations: CRP, C-reactive protein; TNF, tumor necrosis factor; IL, interleukin; Nano-SiO₂, silica nanoparticles; HUVECs, human umbilical vein endothelial cells; ANOVA, one-way analysis of variance; LSD, least significant difference.