Figure 9. Effects of signal pathway inhibitors on the proliferation of NSCs in 4% HCM.

The number of neurospheres was counted at 24 h (A), and the diameters of neurospheres were measured at 48 h (B). DMSO had no effect on NSCs proliferation. The inhibitor LY294002 resulted in a decrease of the number and diameters of neurospheres. ^**p<0.01, SP600125 compared with DMSO; ^ΔΔp<0.01, LY294002 compared with DMSO, ^##p<0.01, LY294002 compared with SP600125 (n = 3).