Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1973 May;7(5):825–826. doi: 10.1128/iai.7.5.825-826.1973

Low-Pathogenicity Variant of Lymphocytic Choriomeningitis Virus

J Hotchin 1, E Sikora 1
PMCID: PMC422768  PMID: 4587522

Abstract

A noncytopathic virus has been isolated from a line of strain L mouse fibroblasts infected with lymphocytic choriomeningitis (LCM). This virus has low pathogenicity for mice and renders them immune to intracerebral challenge with virulent LCM virus.

Full text

PDF
825

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. HOTCHIN J. E., CINITS M. Lymphocytic choriomeningitis infection of mice as a model for the study of latent virus infection. Can J Microbiol. 1958 Apr;4(2):149–163. doi: 10.1139/m58-016. [DOI] [PubMed] [Google Scholar]
  2. HOTCHIN J. The biology of lymphocytic choriomeningitis infection: virus-induced immune disease. Cold Spring Harb Symp Quant Biol. 1962;27:479–499. doi: 10.1101/sqb.1962.027.001.046. [DOI] [PubMed] [Google Scholar]
  3. Hotchin J., Kinch W., Benson L. Lytic and turbid plaque-type mutants of lymphocytic choriomeningitis virus as a cause of neurological disease or persistent infection. Infect Immun. 1971 Sep;4(3):281–286. doi: 10.1128/iai.4.3.281-286.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lehmann-Grube F., Slenczka W., Tees R. A persistent and inapparent infection of L cells with the virus of lymphocytic choriomeningitis. J Gen Virol. 1969 Jul;5(1):63–81. doi: 10.1099/0022-1317-5-1-63. [DOI] [PubMed] [Google Scholar]
  5. SEAMER J., BARLOW J. L., GLEDHILL A. W., HOTCHIN J. INCREASED SUSCEPTIBILITY OF MICE TO LYMPHOCYTIC CHORIOMENINGITIS VIRUS AFTER PERIPHERAL INOCULATION. Virology. 1963 Nov;21:309–316. doi: 10.1016/0042-6822(63)90191-0. [DOI] [PubMed] [Google Scholar]
  6. Staneck L. D., Trowbridge R. S., Welsh R. M., Wright E. A., Pfau C. J. Arenaviruses: cellular response to long-term in vitro infection with parana and lymphocytic choriomeningitis viruses. Infect Immun. 1972 Oct;6(4):444–450. doi: 10.1128/iai.6.4.444-450.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES