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. 2014 Nov 11;9(11):e111215. doi: 10.1371/journal.pone.0111215

Figure 3. SS treatment improves locomotor functions and prolongs lifespan of AD transgenic Drosophila.

Figure 3

(A, C and E) CS, APP/BACE and Aβ transgenic flies were cultured on food containing different concentrations of SS (the triangle symbol stands for concentrations from low to high: 0.2, 0.6 and 2 mg/ml) or Memantine (120 µM). Survival curves for flies treated with either SS or Memantine. The data are presented as mean ± S.E.M. The right panel shows the mean survival days calculated according to the survival curves. (B, D and F) The climbing ability of CS, APP/BACE and Aβ transgenic flies treated with SS or Memantine at day 30 (for CS and APP/BACE flies) and day 20 (for Aβ flies). Values are mean ± S.E.M. Each value represents the mean of three experiments. *P<0.05, **P<0.01, ***P<0.001 vs. Ctrl group. Mem = Memantine.