Figure 2. To examine the expression of the 5-HT_1A receptor across taste receptor cell types, double label immunocytochemistry experiments were performed with alpha-gustducin, a type II cell marker, and NCAM, a type III cell marker.

5-HT_1A-expression extensively overlapped with expression of alpha-gustducin. Illustrated (top) is an example from foliate papillae (FOL). On the other hand, no overlapping expression was observed for 5-HT_1A and NCAM, illustrated at bottom with tissue from the circumvallate papillae (CV). Scale bars are 15 microns.