Table 3. Immunocytochemical cell counts of co-expression patterns of 5HT1A expressing taste receptor cells.
Total tastebuds | 5-HT1Alabeled cells | PhenotypicMarker | Double-labeled cells | Mean 1 (%DL/5-HT1A/TBs/section) ± SE | Mean 2 (%DL/p.m/TBs/section) ± SE | ||
Anterior tongue: fungiform papillae + NID (n = 8 animals) | 5-HT1A/NPY | 120 | 130 | 190 | 95 | 73.08±2.90 | 50.00±9.50 |
5-HT1A/NPY | 60 | 60 | 48 | 36 | 60.00±2.19 | 75.00±0.98 | |
5-HT1A/NPY1R | 48 | 96 | 80 | 56 | 58.33±3.70 | 70.00±2.03 | |
5-HT1A/GUS | 56 | 44 | 96 | 36 | 81.82±0.63 | 37.50±6.93 | |
5-HT1A/CCK-8 | 54 | 48 | 42 | 36 | 75.00±0.98 | 85.71±0.46 | |
Posterior tongue: CV & foliate papillae (n = 8 animals) | 5-HT1A/NPY | 60 | 70 | 142 | 59 | 84.29±0.85 | 41.55±9.11 |
5-HT1A/NPY1R | 84 | 59 | 80 | 46 | 77.97±1.04 | 57.50±3.17 | |
5-HT1A/NCAM | 180 | 135 | 175 | 0 | 0.00 | 0.00 | |
5-HT1A/SNAP | 142 | 150 | 162 | 134 | 89.33±1.20 | 82.72±2.18 | |
5-HT1A/GUS | 92 | 91 | 84 | 63 | 69.23±2.38 | 75.00±1.71 | |
5-HT1A/CCK-8 | 84 | 81 | 138 | 57 | 70.37±0.00 | 41.30±0.00 |