Table 1. The dose-dependent effect of DW-3-15 in oral treatment of mice infected with adult (35-day-old) Schistosoma japonicum at a daily dose of 100–400 mg/kg for 5 days.
dosage (mg/kg per day × day) | control | 100×5 | 200×5 | 400×5 |
Number of mice tested | 10 | 12 | 12 | 12 |
Total worm burden ± s) | 43.0±4.0 | 25.7±6.6 | 18.4±4.3 | 17.5±5.1 |
Total worm reduction (%) | 0 | 40.0* | 56.2* | 58.3* |
*p-value<0.05.