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. 2014 Nov 11;9(11):e112163. doi: 10.1371/journal.pone.0112163

Table 1. The dose-dependent effect of DW-3-15 in oral treatment of mice infected with adult (35-day-old) Schistosoma japonicum at a daily dose of 100–400 mg/kg for 5 days.

dosage (mg/kg per day × day) control 100×5 200×5 400×5
Number of mice tested 10 12 12 12
Total worm burden Inline graphic± s) 43.0±4.0 25.7±6.6 18.4±4.3 17.5±5.1
Total worm reduction (%) 0 40.0* 56.2* 58.3*

*p-value<0.05.