Table 2. Effect of DW-3-15, artesunate and PZQ given orally to mice infected with 14-day-old Schistosoma japonicum at a daily dose of 200 mg/kg for 5 days.
Compound | Number of Mice tested | Total worm burden (![]() |
Total worm reduction (%) |
Control | 10 | 40.8±6.8 | 0 |
DW-3-15 | 12 | 10.5±4.2 | 74.3** |
Artesunate | 12 | 6.8±3.0 | 83.3** |
PZQ | 12 | 34.0±6.6 | 16.2 |
**p-value<0.005.