Table 3. Tandem C–H Fluorination and SNAra.
Isolated yields from the two-step sequence for reactions performed with 0.2 mmol of heteroarene. Yields in parentheses were determined by 19F NMR spectroscopy for the independent fluorination reaction.
The isolated product contained ∼5% of an inseparable impurity.
The Boc group was cleaved during the SNAr reaction.