Figure 2. Phenylephrine-induced vasoconstriction is greater in male than in female mice.

(A) Percent maximal diameter of mesenteric resistance arteries isolated from male and female mice, and exposed to incremental concentrations of phenylephrine. The maximal constriction to phenylephrine was significantly greater (*P≤0.05) in males than females. (B) Percent constriction after exposure to 80 mM KCl of mesenteric resistance arteries isolated from male and female mice. Data are means ± SEM.