Table 2. Correlation between potential non-B DNA regions and gene expression.
| Regions | Expression mean | Expression variation | Expression variation (control for mean) |
|---|---|---|---|
| Random | 0.01 | −0.01 | −0.01 |
| G-quadruplex | 0.04*** | 0.08*** | 0.07*** |
| Z-DNA | 0.09*** | 0.11*** | 0.06*** |
| Slipped DMA | −0.01 | 0.04*** | 0.06*** |
| Cruciform | −0.02** | 0.01 | 0.04*** |
| H-DNA | 0.02** | 0.02** | 0.01 |
| SIDD | −0.02 | −0.02** | −0.00 |
| Nucleotide variants | −0.07*** | −0.03*** | 0.02* |
Spearman rank-order correlations were calculated between the number of potential non-B DNA regions in gene-5′ region of a gene and its expression mean or variation. Random regions and nucleotide variants in gene-5′ regions were used collectively as controls. Significance levels for correlations are categorized as: ***P-value < 0.001; **P-value < 0.01; *P-value < 0.05.