Figure 1.

Genome interactions change throughout the Schizosaccharomyces pombe cell cycle. (A) Significant captured interactions between non-adjacent uniquely positioned restriction fragments were tabulated according to whether they were inter- or intrachromosomal (‘Materials and Methods’ section). Most interactions were intrachromosomal, especially following replication and entry into the G2 and M phases. Intersections between the (Bi) inter- and (Bii) intrachromosomal interactions captured in the three cell cycle phases were calculated and plotted as proportional Venn-diagrams in which the area reflects the number of interactions. (Bi) The majority of captured interchromosomal interactions were specific to one cell cycle phase. (Bii) By contrast, the majority of captured intrachromosomal interactions were shared among the three cell cycle phases.