Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 17;42(20):12833–12846. doi: 10.1093/nar/gku992

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 9. — Arg47, Glu19 and nearby water molecule (peach ball) in the protein chain of the C75U-inhibited structure in the 2Fo-Fc electron density map at 1.2σ contour level. The hydrogen-bonded heavy atoms of Arg47 and Glu19 are highlighted as atom-colored balls. (a) mmm180 rotamer of Arg47 in the original structure (1VC7) clashes with both the water and the backbone of Glu19. (b) mtp180 rotamer of Arg47 in the rebuilt structure (4PRF) now makes hydrogen bonds with both the water and the backbone of Glu19.