Table 4.
Score for isoflavone concentrations in saliva pre- and post intake of isoflavones for dry mouth patients
| Item | Before | After 1 month | After 2 months | Results of two-way repeated measures ANOVA |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Source of variation | SS (Type III) | DF | MF | F | p value | |||||
| Equol (µmol) | Total | 0.27 ± 0.45 | 0.48 ± 1.00 | 0.23 ± 0.53 | Time | 1.148 | 2.000 | 0.574 | 0.418 | 0.664 |
| SS | 0.35 ± 0.55 | 0.64 ± 1.2 | 0.31 ± 0.64 | Time × SS or non-SS | 1.278 | 2.000 | 0.639 | 0.465 | 0.634 | |
| non-SS | 0.13 ± 0.05 | 0.18 ± 0.10 | 0.07 ± 0.05 | SS or non-SS | 0.131 | 1.000 | 0.131 | 0.086 | 0.774 | |
| Daidzein (µmol) | Total | 32 ± 54 | 11 ± 9.8 | 45 ± 55 | Time | 8775.315 | 2.000 | 4387.658 | 3.452 | 0.047* |
| SS | 41 ± 65 | 12 ± 11 | 40 ± 55 | Time × SS or non-SS | 2960.434 | 2.000 | 1480.217 | 1.165 | 0.328 | |
| non-SS | 12 ± 18 | 9.7 ± 7.4 | 54 ± 61 | SS or non-SS | 383.663 | 1.000 | 383.663 | 0.102 | 0.755 | |
| Genistein (µmol) | Total | 47 ± 70 | 20 ± 22 | 64 ± 72 | Time | 14901.865 | 2.000 | 7450.932 | 3.861 | 0.034* |
| SS | 63 ± 82 | 22 ± 25 | 59 ± 69 | Time × SS or non-SS | 6863.201 | 2.000 | 3431.601 | 1.778 | 0.189 | |
| non-SS | 13 ± 15 | 15 ± 13 | 73 ± 84 | SS or non-SS | 1933.870 | 1.000 | 1933.870 | 0.285 | 0.603 | |
Results of two-way repeated measures ANOVA. Values represent the mean ± SD. Total, all subjects; SS, Sjogren’s syndrome group; non-SS, dry mouth group; *Time, p < 0.05. Most of the equol scores were under the limit of detection.