Figure 2. Distribution of differentially regulated miRNAs.

(A) Distribution of differentially regulated miRNAs in mouse kidney cortex 24 h after ¹⁷⁷Lu-octreotate administration (corresponding to absorbed dose to kidney of 0.13–13 Gy). The 0.13 Gy dose level did not share any regulated miRNAs with the other dose levels. Four miRNAs were shared between the groups receiving 0.34, 1.3, 4.3, and 13 Gy. The differential expression levels compared to control of these four miRNAs are shown in (B). * significant expression with p<0.05 and fold-change >1.5.