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. 2014 Nov 11;9(11):e112702. doi: 10.1371/journal.pone.0112702

Table 1. Clinical and demographic data for the study subjects.

No Corticosteroids(n = 244) Corticosteroids(n = 252) P value
Age in years, median (IQR) 2.8 (0.7–7.1) 3.4 (1.3–7.0) 0.097
Males, N (%) 137 (56) 140 (56) 0.966
Deaths, N (%) 21 (9) 43 (17) 0.005
Complicated course, N (%) 53 (22) 80 (32) 0.016
PRISM score, median (IQR) 11 (7–18) 15 (10–22) <0.001
Mean days to death ± SD 5.4±6.8 5.4±5.7 0.955
Median days to death (IQR) 3 (1–17) 4 (1–12) 0.553
PERSEVERE-based mortality probability, mean(95% C.I.) 9.8 (7.9–11.7) 12.7 (10.6–14.8) 0.090
Maximum number of organ failures, median (IQR) 2 (1–3) 2 (2–3) 0.025
Gram-positive bacteria, N (%) 60 (25) 58 (23) 0.759
Number of vasoactive agents at the time ofcorticosteroid initiation, median (IQR) 2 (1–2)
Maximum number of simultaneous vasoactive agentsduring the first 7 days, median (IQR) 1 (1–2) 2 (1–3) <0.001
Gram-negative bacteria, N (%) 45 (18) 58 (23) 0.252
Other organism, N (%) 19 (8) 25 (10) 0.525
Negative cultures, N (%) 120 (49) 111 (44) 0.291
Comorbidity, N (%) 70 (29) 105 (42) 0.003