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. 2014 Nov 11;9(11):e112919. doi: 10.1371/journal.pone.0112919

Table 1. The final population density (N) of species of mites on antibiotic additive diets and fitted concentration EC50 is an effective concentration of antibiotic s in diets for 50% population growth reduction in the comparison to growth on control diet.

Species Antibiotics (mgg−1) Observed data (N) Regression model
0 0.1 1 10 30 R2 a b c Fit EC50 mgg−1
Acarus siro Ampicillin 1183 728 484 275 200 0.95 −2.95 −89 513 0.37
(71) (111) (25) (47) (56) (−3.7/−2.2) (−100/−78) (483 /543) (0.20/0.55)
Neomycin 1179 1059 501 391 304 0.87 −5 −115 689 2.23
(74) (89) (73) (24) (57) (−7/−4) (−133/−96) (640/739) (1.11/3.67)
Streptomycin 1280 1118 883 452 292 0.94 −7 −142 847 4.95
(102) (97) (49) (71) (41) (−8 /−6) (−155/129) (811/882) (3.52/7.03
Lepidoglyphus destructor Ampicillin 1718 1398 1144 603 185 0.87 −10 −202 1060 2.66
(108) (208) (129) (216) (57) (−12/−8) (−231/−173) (982/1139) (1.51/7.03)
Neomycin 1685 414 338 197 116 0.98 2 −56 304 0.0004
(105) (60) (60) (40) (26) (1/3) (−66/−45) (275/332) (0.0001/0.001)
Streptomycin 1685 1465 1106 428 231 0.93 −11 −214 1050 2.38
(96) (218) (161) (68) (51) (−12/−9) (−236/−191) (990/1110) (1.7/3.07)
Tyrophagus putrescentiae Ampicillin 1164 415 297 156 131 0.97 0.1 −51 293 0.003
(95) (36) (18) (20) (18) (−0.4/0.6) (−60/−44) (272/314) (0.001/0.01)
Neomycin 1271 751 639 290 139 0.95 −4 −108 569 0.76
(75) (103) (63) (36) (37) (−5/−3) (−120/−96) (537/602) (0.41/1.21)
Streptomycin 1193 1111 411 355 148 0.85 −7 −140 661 1.58
(98) (144) (48) (41) (16) (−8/−5) (−164/−118) (599/724) (0.74/2.66)

Legend: The final population density is expressed as mean ± standard deviation; the polynomial regression (r = ax2+bx+c; x = antibiotic concentration mgg−1 of diet) describing the suppressive effect of antibiotics to growth rate of tested mites. The antibiotic concentration was transformed logarithmically (LN concentration +1×10−7). The fitted parameters are showed with 95% confidence limits in parenthesis.