Table 3. Signaling Pathways, Biological Processes, and Molecular Functions That Are Targets of R848-Regulated Phosphorylationa.
| enrichment
(p-value) |
|||||
|---|---|---|---|---|---|
| overall | 3 min | 5 min | 10 min | 30 min | |
| (A) Pathway name | |||||
| Rho GTPase signaling | **** | * | ** | * | *** |
| actin cytoskeleton signaling | **** | ** | ** | *** | * |
| phospholipase C signaling | *** | NA | ** | ** | * |
| FAK signaling | *** | ** | * | *** | ** |
| paxilin signaling | *** | *** | *** | ** | *** |
| Cdc42 signaling | NS | ** | ** | ** | NS |
| (B) Gene ontology term | |||||
| cytoskeleton organization | **** | ** | *** | **** | **** |
| cytoskeletal protein binding | **** | * | ** | **** | **** |
| actin binding | **** | *** | *** | **** | *** |
| regulation of Ras protein signal transduction | ** | * | **** | ** | **** |
a
****p < 0.0001. **p < 0.001. **p < 0.01. *p < 0.1.